What exactly happens when you sit in a chair for long hours?
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6) UK Women’s Cohort Study
Sedentary behaviors (including sitting) may increase mortality risk independently of physical activity level as per UK Women’s Cohort Study
According to one of the research “Physiology of sedentary behavior and its relationship to health outcomes” sitting may trigger some genetic factors that are linked to physiological changes.
5) National Library of Medicine, US
7) American Journal of preventive Medicine(AJPM)
Sedentary behaviors (including sitting) may increase mortality risk independently of physical activity level. Little is known about how fidgeting behaviors might modify the association. Source  - AJPM
8) Medical News today
Individuals who sit for several hours of the day not only put themselves at risk for obesity and sore limbs, but also increase their chances of developing kidney disease.
9) CBCnews, Canada
Sitting for too long can kill you, even if you exercise. Higher risk of heart disease, diabetes, cancer, death among those who sit for most of the day: study
As per report publish at Harvard Health Blog - Too much sitting linked to heart disease, diabetes, premature death
10) Harvard Health Blog
• 112% increase in risk of diabetes
• 147% increase in cardiovascular events
1) UK National Research
We all know we need to be active, but there is increasing evidence that we need we spend more time sitting down.
This research has suggested that remaining seated for too long is bad for your health, regardless of how much exercise you do.
Studies have linked excessive sitting with being overweight and obese, type 2 diabetes, some types of cancer, and premature
death. Prolonged sitting is thought to slow the metabolism, which affects the body's ability to regulate blood sugar, blood pressure
and break down body fat.
One of the largest pieces of research to date on the subject - involving almost 800,000 people - found that, compared with those who sat the least, people who sat the longest had a:
We no longer use our bodies as they evolved to be used and no doubt this is having a negative impact on our health which is a leading cause of chronic body ache in addition to dreadful diseases like overweight, Obesity, diabetes, cancer, heart disease and much more.

In following section,10 Medical Evidences are provided about "How sitting long hours is taking toll on our health and fitness"
2) Australian Research
Whether you're a sitting long hours at home watching your favorite TV show or playing games or any other leisure activity or an office worker sitting in front of a computer for long hours, One of the Australian research shows that short break from sitting an hour can ease most of the problems described above.
4) American Heart Association
After Two Weeks of Sitting for More Than Six Hours a Day  - Within five days of changing to a sedentary lifestyle, your body increases plasma triglycerides (fatty molecules), LDL cholesterol (aka bad cholesterol), and insulin resistance. This means your muscles aren't taking in fat and your blood sugar levels go up, putting you at risk for weight gain. After just two weeks your muscles start to atrophy and your maximum oxygen consumption drops.
3) Annals of Internal Medicine
According to the report, published in Annals of Internal Medicine, more than half of the average person’s waking hours are spent sitting: watching television, working at a computer,
This makes stairs harder to climb and walks harder to take. Even if you were working out every day the deterioration starts the second you stop moving.
commuting, or doing other physically inactive pursuits and Prolonged sedentary time was independently associated with deleterious health outcomes regardless of physical activity.
• 90% increase in death caused by cardiovascular events
• 49% increase in death from any cause
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Its all about how you Sit and stay fit
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